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Its use is now one of the standard treatments for erectile dysfunction, including for males with diabetes mellitus. Tentative evidence suggests that sildenafil may help males who experience antidepressant-induced erectile dysfunction.

Route of administration

If you have more questions about how Viagra works, talk with your doctor or pharmacist. Yes, Viagra may help you keep an erection, even after you ejaculate. But if you have an erection that lasts longer than 4 hours, consult a doctor right away. This could be a medical emergency, and it can cause damage to your penis. Viagra can interact with several other medications.

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It can also interact with alcohol and certain foods. Before taking Viagra, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, or supplements you use. Sharing this information can help you avoid potential interactions. While sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects.

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Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon;[9][21] these drugs have moderate efficacy for reducing the frequency and duration of vasospastic episodes. [9] As of 2016,[update] their role more generally in Raynaud's was not clear. Sildenafil has shown some potential for improving exercise performance at high altitudes.

Mechanism of action

These coupons cannot be used with insurance copays or benefits, but the discounted price may be lower than what you would pay through insurance. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. To learn more about Viagra’s price and how to get it, check out these resources: If you have erectile dysfunction, your doctor may recommend that you take Viagra. Be sure to tell your doctor about any medical conditions you have and any medications you take before starting Viagra. Your doctor can determine if this drug is right for you.

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Some questions that you may wish to ask your doctor include: Is Viagra safe for me given my medical history? What’s the best dosage of Viagra for me? What should I do if Viagra doesn’t work? How should I manage side effects of Viagra? To learn more about Viagra, see these articles: Side Effects of Viagra: What You Need to Know Viagra vs. However, its overall efficacy is not clear.

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Sildenafil has been studied for high-altitude pulmonary edema (HAPE), but its use is currently not recommended for that indication.

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Levitra: What You Should Know Will Chewing Up Viagra Make It Work Faster? Comparing Cialis and Viagra: Which One Is Best for You? To get information on different conditions and tips for improving your health, subscribe to any of Healthline’s newsletters. You may also want to check out the online communities at Bezzy. It’s a place where people with certain conditions can find support and connect with others.

What is Viagra (Sildenafil Citrate)?

No, Viagra will not cure ED, but it cenforce 100 soft will help manage its symptoms. Viagra helps to decrease symptoms of ED by helping you to get and keep an erection. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. In clinical trials, the most common adverse effects of sildenafil use included headache, flushing, indigestion, nasal congestion, and impaired vision, including photophobia and blurred vision.

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[4] Some sildenafil users have complained of seeing everything tinted blue (cyanopsia).

Side effects

For a more detailed overview of these interactions and what effects they might cause, see this guide to Viagra interactions. Before taking Viagra, discuss your health history with your doctor. Viagra may not be right for you if you have certain medical conditions or other factors affecting your health. Be sure to talk with your doctor if any of the following apply to you: heart problems, such as a history of heart attack, stroke, or high blood pressure heart surgery within the past 6 months irregular penis shape, such as a curved penis (Peyronie’s disease) blood cell disorders, such as sickle cell anemia or low platelet count previous allergic reaction to Viagra or any of its ingredients Whether you have health insurance or not, cost may be a factor when you’re considering Viagra. What you’ll pay for Viagra may depend on several things, such as your treatment plan and the pharmacy you use.

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Here are a few things to consider regarding cost: Comparing pharmacies: The price of Viagra may vary depending on which pharmacy you use, so it can help to compare prices across pharmacies to find the lowest cost. Generic form: Viagra is available as the generic drug sildenafil. Generics usually cost less than brand-name drugs. Talk with your doctor if you’d like to know whether sildenafil could be an option for you. Drug coupons: You may be able to find drug coupons on prescription discount websites that can reduce the cost of your medication. [24] This cyanopsia can be explained because sildenafil, while selective for PDE5, does have some affinity for PDE6, which is the phosphodiesterase found in the retina. Patients thus taking the drug may experience colorvision abnormalities. Some complained of blurriness and loss of peripheral vision. In July 2005, the US Food and Drug Administration (FDA) updated labeling for tadalafil (Cialis), vardenafil (Levitra), and sildenafil (Viagra) to reflect a small number of post-marketing reports of sudden vision loss, while acknowledging that "...it is not possible to determine whether these oral medicines for erectile dysfunction were the cause of the loss of eyesight or whether the problem is related to other factors such as high blood pressure or diabetes, or to a combination of these problems. "[25] A careful review of pooled data from clinical trials containing well documented information about the dose and duration of exposure to the drug for a large number of patients, yields no evidence for an increased risk of non-arteritic anterior ischemic optic neuropathy or other adverse ocular events associated with PDE5 inhibitor use.

What is "Low T"?

[8] Sildenafil should not be taken by people on nitric oxide donors such as nitroglycerin, as this may result in a serious drop in blood pressure. Sildenafil acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [8] It requires sexual arousal to work, and does not by itself cause or increase sexual arousal. [8] It also results in dilation of the blood vessels in the lungs. Pfizer originally discovered the medication in 1989 while looking for a treatment for angina. Rare but serious adverse effects found through postmarketing surveillance include prolonged erections, severe low blood pressure, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. [4] In October 2007, the FDA announced that the labeling for all PDE5 inhibitors, including sildenafil, required a more prominent warning of the potential risk of sudden hearing loss.

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[11] It was approved for medical use in the United States and in the European Union in 1998. [5][8][11][12] In 2023, it was the 151st most commonly prescribed medication in the United States, with more than 3 million prescriptions. [13][14] It is available as a generic medication. [15][16] In the United Kingdom, it is available as a pharmacy medicine. The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete sexual intercourse). Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects.

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Those using protease inhibitors are recommended to limit their use of sildenafil to no more than one 25 mg dose every 48 hours. [4] Other drugs that interfere with the metabolism of sildenafil include erythromycin and cimetidine, both of which can also lead to prolonged plasma half-life levels.

Why is this medication prescribed?

The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females.

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[8] It can be taken orally (swallowed by mouth), intravenously (injection into a vein), or through the sublingual route (dissolved under the tongue). [8][10] Onset when taken orally is typically within twenty minutes and lasts for about two hours. Common side effects include headaches, heartburn, and flushed skin. [8] Caution is advised in those with cardiovascular disease. [8] Rare but serious side effects include vision problems, hearing loss, and sex with tablet prolonged erection (priapism) that can lead to damage to the penis. The use of sildenafil and an α1 blocker (typically prescribed for hypertension or for urologic conditions, such as benign prostatic hypertrophy) at the same time may lead to low blood pressure, but this effect does not occur if they are taken at least 4 hours apart.