Sildenafil Dosage
[1][7][8][9][10][25][33][34][65][76][81][101][104][105][126][127][131][142][143][144] The erectile response generally increases with increasing sildenafil dose and plasma drug concentration, with response
| Medication Class | Interaction Type | Effect | Clinical Significance |
|---|---|---|---|
| Nitrates | Additive hypotensive effect | Severe hypotension | Contraindicated |
| Alpha-blockers | Enhanced hypotension | Blood pressure drop | Use with caution |
| CYP3A4 inhibitors | Increased sildenafil levels | Prolonged or intensified side effects | Dose adjustment may be needed |
| Protease inhibitors | Elevated sildenafil levels | Increased adverse effects | Monitoring required |
becoming greater at 50- and 100-mg doses than at 25 mg.[1][8][9][33][126][130][131][155] Analyses of subgroups of patients
Further information
Talk to your pharmacist about the potential option(s) noted below. View images of SILDENAFIL CITRATE (Generic for REVATIO) and identify pills by imprint, color or shape. If you need to save money on your SILDENAFIL CITRATE (Generic for REVATIO), compare our prices. Our prescription savings may even be lower than your insurance copay! Note: Multiple images may be displayed for medicines available in different strengths, sold under different brand names, or manufactured by different pharmaceutical companies.
More common
Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a person get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). To decrease your risk of infection, always use an effective barrier method (latex or polyurethane condom/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.
Do Not Take Viagra If You:
25 mg Brand(s): (of Sildenafil Tablets film-coated sildenafil)* Viagra(R), Pfizer 50 mg Brand(s): (of Sildenafil Tablets Pfizer sildenafil)* Viagra(R), Pfizer 100 mg Brand(s): (of Sildenafil Tablets Pfizer sildenafil)* Viagra(R), Pfizer Read the Patient Information Leaflet if available from your pharmacist before you start taking sildenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist. To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before works best). This medication may take longer to start working if you take it with a high-fat meal. with ED indicate that efficacy of sildenafil is not affected by race or age, duration of ED, or duration of select underlying disease states (e.g., diabetes mellitus), and the drug has been effective
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in a broad range of patients with ED, including those with a history of coronary artery disease (e.g., coronary artery bypass graft [CABG]), hypertension, other cardiac disease (including ischemic heart disease), peripheral vascular
8.7 Hepatic Impairment
Do not take more than once daily as needed. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if your condition does not get better. May cause dizziness This drug may impair the ability to operate a vehicle, vessel (e.g., boat), or machinery.
Allergy warning
Use care until you become familiar with its effects. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed sildenafil tablets 125 by your health care professional. Sildenafil is also available in other brands and strengths for high blood pressure in the lungs (pulmonary hypertension). chronic kidney disease stage 4 (severe) GFR 15-29 mL/min chronic kidney disease stage 5 (failure) GFR<15 mL/min kidney disease with likely reduction in glomerular filtration rate (GFR) Drug interactions may change how your medications work or increase your risk for serious side effects.
What does SILDENAFIL CITRATE (Generic for REVATIO) look like?
This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: riociguat, vericiguat. Sildenafil can cause a serious drop in your blood pressure when used with nitrates. disease, type 1 or 2 diabetes mellitus, depression, radical prostatectomy, prostate brachytherapy, transurethral resection of the prostate (TURP), spina bifida, spinal cord injury, and in patients taking antidepressants, antipsychotics, diuretics, and antihypertensive agents.
Dosage And Administration
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of your healthcare professional. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you. You should consult your healthcare professional before taking any drug, changing your diet or commencing or discontinuing any course of treatment. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking any drug or commencing or discontinuing any course of treatment. [1][25][30][33][34][93][101][102][104][105][107][108][112][118][126][127][128][129][130][131][132][133][134][140][144] Pooled data from numerous fixed-dose and flexible-dose studies in men with
- Typical sildenafil dose ranges from 25 to 100 mg.
- It should be taken 30-60 minutes before activity.
- Do not exceed one dose within 24 hours.
ED secondary to a broad spectrum of organic and psychogenic causes showed increases
Why choose us as your Sildenafil manufacturer?
[1][2][4][5][7][8][10][24][27][33][41][56][57][67][91][131] Brand Name: Vybrique, ViagraClasses: Phosphodiesterase Type 5 Inhibitors (24:08.12), Phosphodiesterase type 5 inhibitors (48:48.24) Sildenafil citrate (Viagra® and generic equivalents) is used orally for the treatment of erectile dysfunction (ED, impotence). [1][4][6][7][8][9][10][25][33][34][67][81][102][104][105][107][108][112][118][126][127][128][129][130][131][132][133][134][140][142][143][144][189] A thorough medical, sexual and psychosocial history, physical examination, and selective laboratory testing should be undertaken to diagnose ED, determine potential underlying causes, exclude potentially reversible or treatable causes (e.g., hypogonadism with inadequate testosterone replacement, hyperprolactinemia, drug-induced dysfunction, dyslipidemias, alcoholism, other substance abuse, hypertension, thyroid disease, cardiovascular or cerebrovascular disease, neurologic disease, adrenal dysfunction, psychologic dysfunction, marital discord, smoking), and identify appropriate treatment in conjunction with or prior to initiating vasoactive therapy (e.g., PDE 5 type inhibitor). [12][28][30][31][57][65][66][70][78][83][94][144][145][160][161][189][601][602][603] A review of the patient's current drug regimens should be conducted to detect possible drug-induced ED (e.g., certain antihypertensive, antidepressant, antipsychotic, or antiarrhythmic agents); it may be possible to substitute alternative drug(s) that lessen the risk of such dysfunction. [12][28][70][81][118][144][161][602][603] In instances where substitution therapy is not feasible, concomitant vasoactive therapy with a PDE 5 type inhibitor may promote patient compliance by counteracting ED as an adverse effect. [12][28][70][81][118][144][161][602][603] Efficacy of sildenafil is variable in patients with ED, in part depending on the underlying etiology, severity, and dose employed, but the drug generally appears to be effective in restoring sexual function to an acceptable level in the majority of treated men. in mean rates of successful intercourse (total successes divided by total attempts) to about 66-69% in those receiving sildenafil compared with about 20-22% for placebo.
- Overdose symptoms may include dizziness, nausea, or prolonged erections.
- Seek emergency help if an erection lasts over 4 hours.
- Avoid excessive dosing to prevent adverse events.
Erectile response to sildenafil is better in patients whose erectile function is less impaired at treatment initiation (e.g., those with some spontaneous successful intercourse, with partial erections, with erections during sleep, or with psychogenic causes).
8.4 Pediatric Use
A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called "poppers" containing amyl or butyl nitrite. If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure. Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works.
Take the Next Step Toward Better Performance
Examples sildenafil oral solution include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), mifepristone, rifampin, ritonavir, among others. Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil). Store at room temperature away from light and moisture. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Does Viagra help with premature ejaculation?
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Ask a clinical question and tap into Healio AI's knowledge base. Healio's exclusive daily news coverage of clinical data Selected from data included with permission and copyrighted by FDB, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution in professional health care settings. [1][33][105][145] In one flexible-dose study (dosage titration and maintenance up to 100 mg), mean scores for number of successful penetrations returned to normal in a subgroup
- Using sildenafil with certain medicines can cause serious interactions.
- Blood pressure medications and alpha-blockers are common concerns.
- Always inform your doctor of all medications you're taking.
of patients with psychogenic causes of ED; however, mean scores for maintenance of erections during intercourse in these men were lower than in untreated healthy men.
- Sildenafil is generally safe when used as prescribed.
- Always follow your healthcare provider’s dosage instructions.
- Do not double doses if a dose is missed.
